{"id":3066,"date":"2025-02-14T05:10:28","date_gmt":"2025-02-14T05:10:28","guid":{"rendered":"https:\/\/test.microbac.cl\/english\/?page_id=3066"},"modified":"2025-02-14T05:10:46","modified_gmt":"2025-02-14T05:10:46","slug":"autoimmunity","status":"publish","type":"page","link":"https:\/\/www.microbac.cl\/english\/autoimmunity\/","title":{"rendered":"Autoimmunity"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3066\" class=\"elementor elementor-3066\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9f05aaa elementor-section-full_width elementor-section-height-min-height section-contenedor elementor-section-height-default elementor-section-items-middle\" data-id=\"9f05aaa\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-704c8b8\" data-id=\"704c8b8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-e6f3f03 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e6f3f03\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-a190017\" data-id=\"a190017\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-45f12da elementor-widget elementor-widget-heading\" data-id=\"45f12da\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Autoimmunity<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f805715 section-contenedor elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f805715\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9797962\" data-id=\"9797962\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a4a01a custom-bread elementor-widget elementor-widget-wp-widget-bcn_widget\" data-id=\"7a4a01a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wp-widget-bcn_widget.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Ir a Microbac.\" href=\"https:\/\/www.microbac.cl\/english\" class=\"home\" aria-current=\"page\"><span property=\"name\">Microbac<\/span><\/a><meta property=\"position\" content=\"1\"><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ef8be44 section-contenedor elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ef8be44\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-b3d583b\" data-id=\"b3d583b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-77d67f1 elementor-widget elementor-widget-text-editor\" data-id=\"77d67f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>One of the fundamental properties of the immune system lies in the ability to discriminate between self and non-self antigens. When this self-tolerance is lost, immune reactions against self antigens occur, commonly called autoimmune reactions, which lead to autoimmune diseases.<\/p>\n<p>These diseases are characterized by the spontaneous production of antibodies directed against self antigens. Numerous autoantibodies have been identified, of which only a few are clinically important, affecting 3% to 5% of our general population with a multifactorial etiology that leads to the development of a chronic disease.<\/p>\n<p>Throughout our history, we have been concerned with offering solutions that contribute to the diagnosis and monitoring of these autoimmune diseases.<\/p>\n<p>We have remained attentive to the technological advances of the international market, constantly searching for those solutions, methodologies or instruments that fit the needs of our clients. This is why, within our product portfolio, we offer different diagnostic options; ELISA, Chemiluminescence, both in manual and automated formats.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-6a451bd\" data-id=\"6a451bd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eb9b03a premium-woo-product-align-left lista-productos premium-qv-hidden-yes elementor-widget elementor-widget-premium-woo-products\" data-id=\"eb9b03a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"premium-woo-products.grid-1\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"premium-woocommerce premium-woo-products-grid premium-woo-skin-grid-1 premium-woo-query-custom\" data-page-id=\"3066\" data-skin=\"grid_1\" data-quick-view=\"\"><div class=\"premium-woo-products-inner premium-woo-product__hover-swap\"><ul class=\"products columns-1\">\n\n<li class=\" post-3287 product first instock shipping-taxable product-type-simple\">\n\t\t<div class=\"premium-woo-product-wrapper premium-con-lq__none\">\n\t\t<div class=\"premium-woo-product-thumbnail\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/orgentec-alegria-2-en\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><\/a><\/div><div class=\"premium-woo-products-details-wrap\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/orgentec-alegria-2-en\/\" class=\"premium-woo-product__link\"><h2 class=\"woocommerce-loop-product__title\">Orgentec Alegria\u00ae 2<\/h2><\/a><\/div>\t<\/div>\n<\/li>\n\n<li class=\" post-3291 product first instock shipping-taxable product-type-simple\">\n\t\t<div class=\"premium-woo-product-wrapper premium-con-lq__none\">\n\t\t<div class=\"premium-woo-product-thumbnail\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/orgentec-alegria-1-en\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><\/a><\/div><div class=\"premium-woo-products-details-wrap\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/orgentec-alegria-1-en\/\" class=\"premium-woo-product__link\"><h2 class=\"woocommerce-loop-product__title\">Orgentec Alegria\u00ae 1<\/h2><\/a><\/div>\t<\/div>\n<\/li>\n\n<li class=\" post-469 product first instock shipping-taxable product-type-simple\">\n\t\t<div class=\"premium-woo-product-wrapper premium-con-lq__none\">\n\t\t<div class=\"premium-woo-product-thumbnail\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/immunofluorescence\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><\/a><\/div><div class=\"premium-woo-products-details-wrap\"><a href=\"https:\/\/www.microbac.cl\/english\/producto\/immunofluorescence\/\" class=\"premium-woo-product__link\"><h2 class=\"woocommerce-loop-product__title\">Immunofluorescence<\/h2><\/a><\/div>\t<\/div>\n<\/li>\n<\/ul>\n<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Autoimmunity One of the fundamental properties of the immune system lies in the ability to discriminate between self and non-self antigens. When this self-tolerance is lost, immune reactions against self antigens occur, commonly called autoimmune reactions, which lead to autoimmune diseases. These diseases are characterized by the spontaneous production of antibodies directed against self antigens. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-3066","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"Indirect immunofluorescence (IIF) is one of the most widely used techniques in autoimmunity studies due to its easy handling and standardization. However, its reading and interpretation require extensive experience. The technique is based on the recognition of antibodies that recognize native cellular antigenic structures. The interaction is evidenced by an anti-human immunoglobulin antibody, produced in rabbit, goat or guinea pig, directed against the constant fractions (Fc) of the IgG, IgA and\/or IgM immunoglobulins. Currently, IIF is used in autoimmunity studies for the detection of anti-double-stranded DNA (dsDNA) or native DNA (nDNA) antibodies using Crithidia luciliae as a substrate. For the detection of antibodies that recognize nuclear antigens, human epithelial cell lines such as HEp-2 cells or HeLa cells are used as substrates. In the case of antibodies against components of primary and specific granules of polymorphonuclear cells or anti-neutrophil cytoplasmic antibodies (ANCA), neutrophils fixed with ethanol and formalin are used; and for antibodies that recognize organ-specific antigens, sections of specific tissues are used as substrates (e.g. thyroid, esophagus, stomach, adrenal glands, salivary glands, etc.). Our representatives Scimedx Corporation and Immunoconcepts offer our clients a wide range of substrates and formats for performing autoimmunity diagnosis through immunofluorescence.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.microbac.cl\/english\/producto\/immunofluorescence\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"es_ES\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Microbac - Inicio\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Immunofluorescence - Microbac\" \/>\n\t\t<meta property=\"og:description\" content=\"Indirect immunofluorescence (IIF) is one of the most widely used techniques in autoimmunity studies due to its easy handling and standardization. However, its reading and interpretation require extensive experience. The technique is based on the recognition of antibodies that recognize native cellular antigenic structures. The interaction is evidenced by an anti-human immunoglobulin antibody, produced in rabbit, goat or guinea pig, directed against the constant fractions (Fc) of the IgG, IgA and\/or IgM immunoglobulins. Currently, IIF is used in autoimmunity studies for the detection of anti-double-stranded DNA (dsDNA) or native DNA (nDNA) antibodies using Crithidia luciliae as a substrate. For the detection of antibodies that recognize nuclear antigens, human epithelial cell lines such as HEp-2 cells or HeLa cells are used as substrates. 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Our representatives Scimedx Corporation and Immunoconcepts offer our clients a wide range of substrates and formats for performing autoimmunity diagnosis through immunofluorescence.","og:url":"https:\/\/www.microbac.cl\/english\/producto\/immunofluorescence\/","article:published_time":"2021-12-13T03:38:30+00:00","article:modified_time":"2025-02-20T05:31:02+00:00","twitter:card":"summary_large_image","twitter:title":"Immunofluorescence - Microbac","twitter:description":"Indirect immunofluorescence (IIF) is one of the most widely used techniques in autoimmunity studies due to its easy handling and standardization. However, its reading and interpretation require extensive experience. The technique is based on the recognition of antibodies that recognize native cellular antigenic structures. The interaction is evidenced by an anti-human immunoglobulin antibody, produced in rabbit, goat or guinea pig, directed against the constant fractions (Fc) of the IgG, IgA and\/or IgM immunoglobulins. Currently, IIF is used in autoimmunity studies for the detection of anti-double-stranded DNA (dsDNA) or native DNA (nDNA) antibodies using Crithidia luciliae as a substrate. For the detection of antibodies that recognize nuclear antigens, human epithelial cell lines such as HEp-2 cells or HeLa cells are used as substrates. In the case of antibodies against components of primary and specific granules of polymorphonuclear cells or anti-neutrophil cytoplasmic antibodies (ANCA), neutrophils fixed with ethanol and formalin are used; and for antibodies that recognize organ-specific antigens, sections of specific tissues are used as substrates (e.g. thyroid, esophagus, stomach, adrenal glands, salivary glands, etc.). Our representatives Scimedx Corporation and Immunoconcepts offer our clients a wide range of substrates and formats for performing autoimmunity diagnosis through immunofluorescence."},"aioseo_meta_data":{"post_id":"3066","title":null,"description":null,"keywords":null,"keyphrases":{"focus":{"keyphrase":"","score":0,"analysis":{"keyphraseInTitle":{"score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"WebPage","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"breadcrumb_settings":null,"limit_modified_date":false,"ai":null,"created":"2025-02-14 05:07:45","updated":"2025-07-04 17:30:18","seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.microbac.cl\/english\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tAutoimmunity\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.microbac.cl\/english"},{"label":"Autoimmunity","link":"https:\/\/www.microbac.cl\/english\/autoimmunity\/"}],"_links":{"self":[{"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/pages\/3066","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/comments?post=3066"}],"version-history":[{"count":0,"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/pages\/3066\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.microbac.cl\/english\/wp-json\/wp\/v2\/media?parent=3066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}